The result demonstrated that with the molecule we were using, the way that finally proved to be promising, it was not effective, even deleterious. This result was important as it allowed this molecule to not be used.
Boissel JP, Auffray C, Denis Noble, Hood L, Boissel FH | CPT Pharmacometrics Syst. Pharmacol 2015; 4, e26
Comparison of an effect-model-law based method versus traditional clinical practice guidelines for optimal treatment decision-making: application to statin treatment in the French population
Kahoul R, Gueyffier F, Amsallem E, Haugh M, Marchant I, Boissel FH, Boissel JP | J.R. Soc. Interface 2014; 11, 100: 20149867
Boissel JP, Kahoul R, Draltan M, Boissel FH | J. Pers. Med 2013; 3, 177-190
Clinical trial simulation using therapeutic effect modelling: application to ivabradine efficacy in patients with angina pectoris
Chabaud S, Girard P, Nony P, Boissel JP | J of Pharmacokinetics and Pharmacodynamics 2002; 29: 339-63